Cambridge BRC

Capacity & Development - Recent Papers

Marian Burr

HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation

Burr ML, Cano F, Svobodova S, Boyle LH, Boname JM, Lehner PJ.

Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2034-9. Epub 2011 Jan 18.

Stella Calafato

The GENCODE exome: sequencing the complete human genome

Coffey AJ, Kokocinski F, Calafato MS, Scott CE, Palta P, Drury E, Joyce CJ, Leproust EM, Harrow J, Hunt S, Lehesjoki AE, Turner DJ, Hubbard TJ, Palotie A

Eur J Hum Genet. 2011 Mar 2. [Epub ahead of print]

International Headache Genetics Consortium. Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1

Anttila V, Stefansson H, Kallela M, Todt U, Terwindt GM, Calafato MS, Nyholt DR, Dimas AS, Freilinger T, M'ller-Myhsok B, Artto V, Inouye M, Alakurtti K, Kaunisto MA, H'm'l'inen E, de Vries B, Stam AH, Weller CM, Heinze A, Heinze-Kuhn K, Goebel I, Borck G, G'bel H, Steinberg S, Wolf C, Bj'rnsson A, Gudmundsson G, Kirchmann M, Hauge A, Werge T, Schoenen J, Eriksson JG, Hagen K, Stovner L, Wichmann HE, Meitinger T, Alexander M, Moebus S, Schreiber S, Aulchenko YS, Breteler MM, Uitterlinden AG, Hofman A, van Duijn CM, Tikka-Kleemola P, Veps'l'inen S, Lucae S, Tozzi F, Muglia P, Barrett J, Kaprio J, F'rkkil' M, Peltonen L, Stefansson K, Zwart JA, Ferrari MD, Olesen J, Daly M, Wessman M, van den Maagdenberg AM, Dichgans M, Kubisch C, Dermitzakis ET, Frants RR, Palotie A;

Nat Genet. 2010 Oct;42(10):869-73

John Cannon

Intersegmental vessel formation in zebrafish: requirement for VEGF but not BMP signalling revealed by selective and non-selective BMP antagonists

CANNON, J. E., UPTON, P. D., SMITH, J. C. & MORRELL, N. W.

(2010) Br J Pharmacol, 161, 140-9.

Jatinder Juss

Effects of the cyclin-dependent kinase inhibitor R-roscovitine on eosinophil survival and clearance

Farahi N, Uller L, Juss JK, Langton AJ, Cowburn AS, Gibson A, Foster MR, Farrow SN, Marco-Casanova P, Sobolewski A, Condliffe AM, Chilvers ER

Clin Exp Allergy. 2011 Jan 24. doi: 10.1111/j.1365-2222.2010.03680.x. [Epub ahead of print]

Interleukin-5 inhibits glucocorticoid-mediated apoptosis in human eosinophils

Brode S, Farahi N, Cowburn AS, Juss JK, Condliffe AM, Chilvers ER

Thorax. 2010 Dec;65(12):1116-7. Epub 2010 Aug 30

Alastair Lamb

Meta-analysis showing the beneficial effect of a-blockers on ureteric stent discomfort

Lamb AD, Vowler SL, Johnston R, Dunn N, Wiseman OJ

BJU Int. 2011 Mar 31. doi: 10.1111/j.1464-410X.2011.10170.x. [Epub ahead of print].

CD4+ and CD8+ T-lymphocyte scores cannot reliably predict progression in patients with benign prostatic hyperplasia (BPH)

Lamb AD, Qadan M, Roberts S, Timlin H, Vowler SL, Campbell FM, Grigor K, Bartlett JM, McNeill SA

BJU Int. In print. "Best of BAUS 2009".

Pre-malignant disease of the prostate. In: Advances in Understanding the Basic Pathogenesis and Clinical Management of Pre-Invasive Disease

Lamb AD, Warren AY, Neal DE. Ch

Edited Fitzgerald, RC. Springer Publishing Company. In print. DOI 10.1007/978-1-4419-6694-0_22, ' Springer Science+Business Media, LLC 2010

How effective is self-management for men with lower urinary tract symptoms?

Dunn N, Lamb AD

Trends in Urology, Gynaecology & Sexual Health. 2009 Oct;14(5):4 5

"Holmium laser enucleation of the prostate (HoLEP) is safe and efficacious in treatment of urinary retention."

Lamb AD, Shukla CJ, Rochester MA, Mathias S, Akhtar M, Aho TF. "Best of BAUS 2008".

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Highlights Urological Cancer: David Neal Funding from the BRC has been used to develop and support the biorepository and to ensure optimum collection of tissue for translational research into prostate cancer. Read more...