Cambridge BRC

03. Diabetes, Obesity, Metabolism and Endocrinology - Key Publications

  1. 1. Beardsall K et al. (2008) Early insulin therapy in very-low-birth-weight infants. N Engl J Med. 359:1873-84.
  2. Dash S et al. (2009) A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia. Proc Natl Acad Sci U S A. 106(23):9350-5.
  3. Greenfield JR et al. (2009) Modulation of blood pressure by central melanocortinergic pathways. N Engl J Med 360(1):44-52.
  4. Semple RK et al. (2009) Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis. J Clin Invest. 119(2):315-22.
  5. Topaloglu AK et al. (2009) Loss-of-function mutations in TAC3 or TACR3, encoding neurokinin B and its receptor, produce hypogonadotropic hypogonadism in humans. Nat. Genet. 41:354-8.
  6. Bochukova EG et al. (2010) Large, rare chromosomal deletions associated with severe earlyonset obesity. Nature 463(7281):666-70.
  7. Mitchell CS, et al. Resistance to thyroid hormone is associated with raised energy expenditure, muscle mitochondrial uncoupling, and hyperphagia. J Clin Invest. 2010 Apr 1;120(4):1345-54. doi: 10.1172/JCI38793.
  8. Hovorka R et al. (2010) Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial. Lancet 375(9716):743-51.
  9. Regan FM, et al. (2010) Treatment with Recombinant Human Insulin-like Growth Factor (rhIGF)-1/rhIGF Binding Protein-3 Complex Improves Metabolic Control in Subjects with Severe Insulin Resistance. J Clin Endocrinol Metab. 95(5):2113-22.
  10. Walters RG, et al. (2010) A new highly penetrant form of obesity due to deletions on chromosome 16p11.2. Nature. 2010 Feb 4;463(7281):671-5.
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Highlights DOME Members Receive Awards Two members of the DOME theme, Professor Steve O'Rahilly (theme leader) and Professor Krishna Chatterjee are among the first to be awarded Wellcome Trust Senior Investigator Awards, a prestigious new scheme providing funding for exceptional researchers who demonstrate they are addressing some of the most important questions about health and disease. Read more...