Cambridge BRC

04. Imaging - Key Publications

  1. Barrett, T., Bowden, D. J., Greenberg, D. C., Brown, C. H., Wishart, G. C. & Britton, P. D. 2009. Radiological staging in breast cancer: which asymptomatic patients to image and how. Br J Cancer, 101(9), Nov 3, 1522-8.
  2. Evans DG, Lennard F, Pointon LJ, Ramus SJ, Gayther SA, Sodha N, Kwan-Lim GE, Leach MO, Warren R, Thompson D, Easton DF, Eeles R; 2009. UK Study of MRI Screening for Breast Cancer in Women at High Risk (MARIBS). Eligibility for magnetic resonance imaging screening in the United Kingdom: effect of strict selection criteria and anonymous DNA testing on breast cancer incidence in the MARIBS Study. Cancer Epidemiol Biomarkers Prev. 2009 Jul;18(7):2123-31.
  3. Sadat, U., Weerakkody, R. A., Bowden, D. J., Young, V. E., Graves, M. J., Li, Z. Y., Tang, T. Y., Gaunt, M. E., Hayes, P. D. & Gillard, J. H. 2009. Utility of high resolution MR imaging to assess carotid plaque morphology: a comparison of acute symptomatic, recently symptomatic and asymptomatic patients with carotid artery disease. Atherosclerosis, 207(2), Dec, 434-9.
  4. Mannelli, L., E. Godfrey, I. Joubert, A.J. Patterson, M.J. Graves, F.A. Gallagher, and D.J. Lomas, 2010. MR elastography: Spleen stiffness measurements in healthy volunteers'preliminary experience. AJR Am J Roentgenol, 195(2): p. 387-92.
  5. Horsfield, M. A., Thornton, J. S., Gill, A., Jager, H. R., Priest, A. N. & Morgan, B. 2009. A functional form for injected MRI Gd-chelate contrast agent concentration incorporating recirculation, extravasation and excretion. Phys Med Biol, 54(9), May 7, 2933-49.
  6. Graves, M. J., Wong, P., Priest, A. N., Black, R. T. & Lomas, D. J. 2009. Slice offset frequency and shim adjustment for interactive steady-state free-precession (SSFP) imaging. J Magn Reson Imaging, 29(5), May, 1230-3.
  7. Graves, M. J., Black, R. T. & Lomas, D. J. 2009. Constrained surface controllers for three-dimensional image data reformatting. Radiology, 252(1), Jul, 218-24.
  8. Gallagher, F. A., Kettunen, M. I., Hu, D. E., Jensen, P. R., Zandt, R. I., Karlsson, M., Gisselsson, A., Nelson, S. K., Witney, T. H., Bohndiek, S. E., Hansson, G., Peitersen, T., Lerche, M. H. & Brindle, K. M. 2009. Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors. Proc Natl Acad Sci U S A, 106(47), Nov 24, 19801-06.
  9. Paulmurugan, R., Padmanabhan, P., Ahn, B. C., Ray, S., Willmann, J. K., Massoud, T. F., Biswal, S. & Gambhir, S. S. 2009. A novel estrogen receptor intramolecular folding-based titratable transgene expression system. Mol Ther, 17(10), Oct, 1703-11.
  10. Massoud TF, Paulmurugan R, Gambhir SS. 2010. A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography. Nat Med. Aug;16(8):921-6.
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Highlights Clinical Impact Studies This year has seen previous radiology publications cited in guidelines for breast cancer (www.nice.org.uk) prostate cancer (www.uroweb.org) & pleural procedures. Related current studies in breast cancer screening and evaluation of carotid artery disease have been completed. More than 50 Oncology trials using CT,RECIST measurements are currently active.