Recent Publications

1. Matthews FE, Arthur A, Barnes LE, Bond J, Jagger C, Robinson L, Brayne C; Medical Research Council Cognitive Function and Ageing Collaboration. A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II. Lancet. 2013 Oct 26;382(9902):1405-12. doi: 10.1016/S0140-6736(13)61570-6.

2. Davison, C. M., & O'Brien, J. T. (2013). A comparison of FDG-PET and blood flow SPECT in the diagnosis of neurodegenerative dementias: a systematic review. Int J Geriatr Psychiatry. doi:10.1002/gps.4036

3. Ye, Z., Altena, E., Nombela, C., Housden, C.R., Maxwell, H., Rittman, T., Huddleston, C., Rae, C.L., Regenthal, R., Sahakian, B.J., Barker, R.A., Robbins, T.W., Rowe, J.B. (accepted). 'Selective serotonin reuptake inhibition modulates response inhibition in Parkinson’s disease', Brain. In press 2014.

4. Zheng Ye, Ellemarije Altena, Cristina Nombela, Charlotte R Housden, Helen Maxwell, Timothy Rittman, Chelan Huddleston, Charlotte L Rae, Ralf Regenthal, Barbara J Sahakian, Roger A Barker, Trevor W Robbins, James B Rowe. Improving response inhibition in Parkinson's disease with Atomoxetine. Biological Psychiatry. In press 2014.

5. M Renna, C Figueira-Bento, A Fleming, FM Menzies, FH Siddiqi, B Ravikumar, C Puri, M Garcia-Arencibia, O Sadiq, S Corrochano, S Carter, SDM Brown, A Acevedo-Arozena and DC Rubinsztein (2013) IGF-1 Receptor Antagonism Inhibits Autophagy. Human Molecular Genetics 22:4528-44

6. J-C Lambert… DC Rubinsztein, PH St George-Hyslop,P Amouyel (2013) Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nature Genetics 45:1452-8

7. Palfi S, Gurruchaga JM, Ralph GS, Lepetit H, Lavisse S, Buttery PC, Watts C, Miskin J, Kelleher M, Deeley S, Iwamuro H, Lefaucheur JP, Thiriez C, Fenelon G, Lucas C, Brugières P, Gabriel I, Abhay K, Drouot X, Tani N, Kas A, Ghaleh B, Le Corvoisier P, Dolphin P, Breen DP, Mason S, Guzman NV, Mazarakis ND, Radcliffe PA, Harrop R, Kingsman SM, Rascol O, Naylor S, Barker RA, Hantraye P, Remy P, Cesaro P, Mitrophanous KA. Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial. Lancet. 2014 Jan 9. pii: S0140-6736(13)61939-X.

8. Begeti F, Tan AY, Cummins GA, Collins LM, Guzman NV, Mason SL, Barker RA. The Addenbrooke's Cognitive Examination-Revised accurately detects cognitive decline in Huntington's disease. J Neurol. 2013 Nov;260(11):2777-85.

9. Cruchaga C... St George-Hyslop P, Cairns N, Morris JC, Kauwe JS, Goate AM. Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease. Nature. 2014 505:550-554.

10. Guerreiro R... St George-Hyslop P, Singleton A, Hardy J; Alzheimer Genetic Analysis Group. TREM2 variants in Alzheimer's disease. N Engl J Med. 2013 368:117-127.